We have developed a method (MAD) to detect genetic mosaicisms using SNP array data that has been used to assess association between mosaicisms and aging, cancer, and other disorders. We have also created a new package to call loss of chromosome Y (MADloy) using SNP array data that is being used in large cohorts to asses association between LOY and complex diseases. Furthermore, we are working on a new package to call loff of chromosome Y based on whole genome sequencing data (MADseqLOY).
